Comparative Physical Study of Three Pharmaceutically Active Benzodiazepine Derivatives: Crystalline versus Amorphous State and Crystallization Tendency

Comparative Physical Study of Three Pharmaceutically Active Benzodiazepine Derivatives: Crystalline versus Amorphous State and Crystallization Tendency

by

Chemical derivatization and amorphization are two doable methods to enhance the solubility and bioavailability of medication, which is a key subject for the pharmaceutical trade. In this contribution, we discover whether or not each methods might be mixed by finding out how small variations within the molecular construction of three associated pharmaceutical compounds have an effect on their crystalline construction and melting level (Tm), the relief dynamics within the amorphous part, and the glass transition temperature (Tg), in addition to the tendency towards recrystallization. Three benzodiazepine derivatives of virtually similar molecular mass and construction (Diazepam, Nordazepam and Tetrazepam) had been chosen as mannequin compounds.

Nordazepam is the one one which shows N-H···O hydrogen bonds each in crystalline and amorphous phases, which ends up in a considerably larger Tm (by 70-80 Ok) and Tg (by 30-40 Ok) in comparison with these of Tetrazepam and Diazepam (which show comparable values of attribute temperatures). The rest dynamics within the amorphous part, as decided experimentally utilizing broadband dielectric spectroscopy, is dominated by a structural rest and a Johari-Goldstein secondary rest, each of which scale with the decreased temperature T/Tg. The kinetic fragility index could be very low and nearly the identical (mp ≈ 32) in all three compounds.

Two extra secondary relaxations are noticed within the glass state: the slower of the 2 has nearly the identical rest time and activation power in all three compounds, and is assigned to the inter-enantiomer conversion dynamics of the versatile diazepine heterocycle between isoenergetic P and M conformations. We tentatively assign the quickest secondary rest, current solely in Diazepam and Tetrazepam, to the inflexible rotation of the fused diazepine-benzene double ring relative to the six-membered carbon ring. Such movement seems to be largely hindered in glassy Nordazepam, presumably because of the presence of the hydrogen bonds.

Supercooled liquid Tetrazepam and Nordazepam are noticed to crystallize into their steady crystalline type with an Avrami exponent near unity indicating unidimensional progress with solely sporadic nucleation, which permits a direct evaluation of the crystal progress price. Despite the very comparable progress mode, the 2 derivatives exhibit very totally different kinetics for a set worth of the decreased temperature and thus of the structural rest time, with Nordazepam displaying slower progress kinetics.

Diazepam doesn’t as a substitute show any tendency towards recrystallization over quick durations of time (even near Tm). Both these observations in three very comparable diazepine derivatives present direct proof that the kinetics of recrystallization of amorphous prescribed drugs shouldn’t be a common perform, no less than within the supercooled liquid part, of the structural or the conformational rest dynamics, and it isn’t merely correlated with associated parameters such because the kinetic fragility or activation barrier of the structural rest. Only the crystal progress price, and not the nucleation price, exhibits a correlation with the presence or absence of hydrogen bonding.

Searching for situations of protein self-assembly by protein crystallization screening technique

The self-assembly of biomacromolecules is a particularly vital course of. It is doubtlessly helpful within the fields of life science and supplies science. To perform the examine on the self-assembly of proteins, it’s essential to seek out out the acceptable self-assembly situations, which have all the time been a difficult activity in follow. Inspired by the screening approach within the subject of protein crystallization, we proposed utilizing the identical screening approach for in search of appropriate protein self-assembly situations. Based on this consideration, we chosen 5 proteins (β-lactoglobulin, hemoglobin, pepsin, lysozyme, α-chymotrypsinogen (II) A) along with 5 screening kits (IndexTM, BML, Morpheus, JCSG, PEG/Ion ScreenTM) to research the efficiency of these crystallization screening methods with a view to uncover new optimized situations of protein self-assembly.

The screens had been all stored at 293 Ok for sure days, and had been analyzed utilizing optical microscope, scanning electron microscope, transmission electron microscope, atomic pressure microscope, fluorescence microscope, and atomic absorption spectroscope. The outcomes demonstrated that the tactic of protein crystallization screening might be efficiently utilized within the screening of self-assembly situations. This technique is quick, excessive throughput, and simply carried out in an automatic system, with a low protein consumption function.

These outcomes prompt that such technique might be utilized to discovering new situations or types in routine analysis of protein self-assembly. KEY POINTS: • Protein crystallization screening technique is efficiently utilized within the screening of self-assembly situations. • This screening technique might be utilized on numerous varieties of proteins and possess a function of low protein consumption. • This screening technique is quick, excessive throughput, and simply carried out in an automatic system.

Comparative Physical Study of Three Pharmaceutically Active Benzodiazepine Derivatives: Crystalline versus Amorphous State and Crystallization Tendency

Effect of Freeze Crystallization on Quality Properties of Two Endemic Patagonian Berries Juices: Murta ( Ugni molinae) and Arrayan ( Luma apiculata)

This work studied the results of centrifugal block freeze crystallization (CBFC) on physicochemical parameters, complete phenolic compound content material (TPCC), antioxidant exercise (AA), and course of parameters utilized to recent murta and arrayan juices. In the final cycle, for recent murta and arrayan juices, the overall soluble solids (TSS) confirmed values near 48 and 54 Brix, and TPCC exhibited values of roughly 20 and 66 mg gallic acid equivalents/100 grams dry matter (d.m.) for complete polyphenol content material, 13 and 25 mg cyanidin-3-glucoside equivalents/100 grams d.m. for complete anthocyanin content material, and 9 and 17 mg quercetin equivalents/100 grams d.m. for complete flavonoid content material, respectively.

ELISA kit for Human Structural maintenance of chromosomes protein 4
EK4589 96 tests
EUR 603
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Structural maintenance of chromosomes protein 4 in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Mouse BFSP1 (Beaded Filament Structural Protein 1)
ELK7349 1 plate of 96 wells
EUR 432
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Beaded Filament Structural Protein 1 (BFSP1). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody s
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Description: A sandwich ELISA kit for detection of Beaded Filament Structural Protein 1 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Recombinant MAYV Structural polyprotein Protein
VAng-Wyb3702-inquire inquire Ask for price
Description: Mayaro virus (strain Brazil) Structural polyprotein, recombinant protein.

ELISA kit for Rat Meiosis-specific nuclear structural protein 1 (MNS1)
KTE100598-48T 48T
EUR 332
  • MNS1 encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may function as a nuclear skeletal protein to regulate nuc
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Description: Quantitative sandwich ELISA for measuring Rat Meiosis-specific nuclear structural protein 1 (MNS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Meiosis-specific nuclear structural protein 1 (MNS1)
KTE100598-5platesof96wells 5 plates of 96 wells
EUR 2115
  • MNS1 encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may function as a nuclear skeletal protein to regulate nuc
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Description: Quantitative sandwich ELISA for measuring Rat Meiosis-specific nuclear structural protein 1 (MNS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Meiosis-specific nuclear structural protein 1 (MNS1)
KTE100598-96T 96T
EUR 539
  • MNS1 encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may function as a nuclear skeletal protein to regulate nuc
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Description: Quantitative sandwich ELISA for measuring Rat Meiosis-specific nuclear structural protein 1 (MNS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Meiosis-specific nuclear structural protein 1 (MNS1)
KTE10284-48T 48T
EUR 354
  • Meiosis-specific nuclear structural protein 1 (MNS1) encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may functi
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Description: Quantitative sandwich ELISA for measuring Bovine Meiosis-specific nuclear structural protein 1 (MNS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Meiosis-specific nuclear structural protein 1 (MNS1)
KTE10284-5platesof96wells 5 plates of 96 wells
EUR 2252
  • Meiosis-specific nuclear structural protein 1 (MNS1) encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may functi
  • Show more
Description: Quantitative sandwich ELISA for measuring Bovine Meiosis-specific nuclear structural protein 1 (MNS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Meiosis-specific nuclear structural protein 1 (MNS1)
KTE10284-96T 96T
EUR 572
  • Meiosis-specific nuclear structural protein 1 (MNS1) encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may functi
  • Show more
Description: Quantitative sandwich ELISA for measuring Bovine Meiosis-specific nuclear structural protein 1 (MNS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Meiosis-specific nuclear structural protein 1 (MNS1)
KTE70991-48T 48T
EUR 332
  • MNS1 encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may function as a nuclear skeletal protein to regulate nuc
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Meiosis-specific nuclear structural protein 1 (MNS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Meiosis-specific nuclear structural protein 1 (MNS1)
KTE70991-5platesof96wells 5 plates of 96 wells
EUR 2115
  • MNS1 encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may function as a nuclear skeletal protein to regulate nuc
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Meiosis-specific nuclear structural protein 1 (MNS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Meiosis-specific nuclear structural protein 1 (MNS1)
KTE70991-96T 96T
EUR 539
  • MNS1 encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may function as a nuclear skeletal protein to regulate nuc
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Meiosis-specific nuclear structural protein 1 (MNS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Meiosis-specific nuclear structural protein 1 (MNS1)
KTE61577-48T 48T
EUR 332
  • MNS1 encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may function as a nuclear skeletal protein to regulate nuc
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Meiosis-specific nuclear structural protein 1 (MNS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Meiosis-specific nuclear structural protein 1 (MNS1)
KTE61577-5platesof96wells 5 plates of 96 wells
EUR 2115
  • MNS1 encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may function as a nuclear skeletal protein to regulate nuc
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Meiosis-specific nuclear structural protein 1 (MNS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Meiosis-specific nuclear structural protein 1 (MNS1)
KTE61577-96T 96T
EUR 539
  • MNS1 encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may function as a nuclear skeletal protein to regulate nuc
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Meiosis-specific nuclear structural protein 1 (MNS1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Recombinant TBEV Non-Structural Protein 3
VAng-Lsx0520-inquire inquire Ask for price
Description: TBEV Non-structural Protein 3, recombinant protein from E. coli.

Structural Polyprotein (VP2) Antibody
abx224337-100ug 100 ug
EUR 411
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Sindbis virus Structural polyprotein
1-CSB-CF361018SHZ
  • EUR 1363.00
  • EUR 637.00
  • EUR 893.00
  • 1MG
  • 200ug
  • 500ug
  • MW: 67.4 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Sindbis virus Structural polyprotein,partial expressed in in vitro E.coli expression system

Sindbis virus Structural polyprotein
1-CSB-CF361018SHZb2
  • EUR 1363.00
  • EUR 637.00
  • EUR 893.00
  • 1MG
  • 200ug
  • 500ug
  • MW: 65.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Sindbis virus Structural polyprotein,partial expressed in in vitro E.coli expression system

Recombinant CHIKV Structural Polyprotein
VAng-Lsx0030-inquire inquire Ask for price
Description: CHIKV Structural Polyprotein, recombinant protein from E. coli.

Foot-and-Mouth Disease Virus Non-Structural Protein 2a (FMDV Non-Structural Protein 2a) Antibody
abx414630-02mg 0.2 mg
EUR 565
  • Shipped within 1 week.

Holder for Plasmid Midi, Maxi and Maxi plus, Ion Exchange column
FAPDE-holder-for-ion-exchange 1 prep
EUR 158

Beaded Filament Structural Protein 1 (BFSP1) Antibody
20-abx175558
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug
  • Please enquire.

Beaded Filament Structural Protein 1 (BFSP1) Antibody
20-abx111214
  • EUR 732.00
  • EUR 398.00
  • 150 ul
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Yellow Fever Non-Structural Protein 1 (NS1) Protein
abx160019-1mg 1 mg
EUR 1442
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Mouse Beaded Filament Structural Protein 1 (BFSP1) Protein
20-abx652653
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
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Recombinant CHIKV Non-structural Polyprotein
VAng-Lsx0031-1mgEcoli 1 mg (E. coli)
EUR 4168
Description: CHIKV Non-structural Polyprotein, recombinant protein from E. coli.

Recombinant CHIKV Non-structural Polyprotein
VAng-Lsx0031-500gEcoli 500 µg (E. coli)
EUR 2788
Description: CHIKV Non-structural Polyprotein, recombinant protein from E. coli.

T4 gp32 Protein- 500µg
3515 1/EA
EUR 346

T4 UvsY Protein - 100µg
3572 1/EA
EUR 357

T4 UvsY Protein - 500µg
3575 1/EA
EUR 752

Human Structural Maintenance Of Chromosomes Protein 3 (SMC3) Protein
20-abx069182
  • EUR 732.00
  • EUR 286.00
  • EUR 2263.00
  • EUR 871.00
  • EUR 523.00
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Influenza B virus Non-structural protein 1 (NS)
1-CSB-EP365963IJK
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 36.1 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Influenza B virus Non-structural protein 1(NS) expressed in E.coli

Influenza A virus Non-structural protein 1 (NS)
1-CSB-EP604972IER
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 30.8 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Influenza A virus Non-structural protein 1(NS) expressed in E.coli

Influenza B virus Non-structural protein 1 (NS)
1-CSB-YP319433IJV
  • EUR 586.00
  • EUR 299.00
  • EUR 2172.00
  • EUR 900.00
  • EUR 1442.00
  • EUR 382.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 34.2 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Influenza B virus Non-structural protein 1(NS) expressed in Yeast

Influenza B virus Non-structural protein 1 (NS)
1-CSB-YP365963IJK
  • EUR 586.00
  • EUR 299.00
  • EUR 2172.00
  • EUR 900.00
  • EUR 1442.00
  • EUR 382.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 34.1 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Influenza B virus Non-structural protein 1(NS) expressed in Yeast

Influenza A virus Non-structural protein 1 (NS)
1-CSB-YP604972IER
  • EUR 586.00
  • EUR 299.00
  • EUR 2172.00
  • EUR 900.00
  • EUR 1442.00
  • EUR 382.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 28.8 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Influenza A virus Non-structural protein 1(NS) expressed in Yeast

Dengue Virus Non-Structural Protein 1 (NS1) Antibody
abx024080-1mg 1 mg
EUR 1024
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Dengue Virus Non-Structural Protein 1 (NS1) Antibody
abx024081-1mg 1 mg
EUR 1024
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes Protein 1A (SMC1) Antibody
abx015996-100ul 100 ul
EUR 411
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes Protein 3 (SMC3) Antibody
20-abx218673
  • EUR 425.00
  • EUR 342.00
  • 100 ug
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Structural maintenance of chromosomes protein 4 (SMC4) Antibody
20-abx211663
  • EUR 411.00
  • EUR 300.00
  • 100 ul
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Structural maintenance of chromosomes protein 4 (SMC4) Antibody
20-abx211867
  • EUR 411.00
  • EUR 300.00
  • 100 ul
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Structural Maintenance of Chromosomes Protein 3 (SMC3) Antibody
20-abx104450
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
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  • Shipped within 5-7 working days.

Structural Maintenance of Chromosomes Protein 3 (SMC3) Antibody
abx122463-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes Protein 1A (SMC1) Antibody
20-abx012879
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes Protein 3 (SMC3) Antibody
abx028345-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes Protein 3 (SMC3) Antibody
abx028345-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes Protein 3 (SMC3) Antibody
abx238017-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Structural Maintenance of Chromosomes Protein 4 (SMC4) Antibody
abx238018-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Meiosis-Specific Nuclear Structural Protein 1 (MNS1) Antibody
abx235256-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

Structural maintenance of chromosomes protein 4 (SMC4) Antibody
20-abx333908
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
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  • Shipped within 5-10 working days.

Recombinant human Structural maintenance of chromosomes protein 1B
P2237 100ug Ask for price
  • Uniprot ID: Q8NDV3
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)
Description: Recombinant protein for human Structural maintenance of chromosomes protein 1B

Recombinant human Structural maintenance of chromosomes protein 5
P2825 100ug Ask for price
  • Uniprot ID: Q8IY18
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)
Description: Recombinant protein for human Structural maintenance of chromosomes protein 5

Recombinant human Structural maintenance of chromosomes protein 6
P2826 100ug Ask for price
  • Uniprot ID: Q96SB8
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)
Description: Recombinant protein for human Structural maintenance of chromosomes protein 6

Recombinant MAYV Structural polyprotein Protein (aa 807-1242)
VAng-Wyb3704-100g 100 µg
EUR 6897
Description: Mayaro virus (strain Brazil) Structural polyprotein, recombinant protein.

Recombinant MAYV Structural polyprotein Protein (aa 807-1242)
VAng-Wyb3704-10g 10 µg
EUR 3005
Description: Mayaro virus (strain Brazil) Structural polyprotein, recombinant protein.

Recombinant MAYV Structural polyprotein Protein (aa 807-1242)
VAng-Wyb3704-50g 50 µg
EUR 4394
Description: Mayaro virus (strain Brazil) Structural polyprotein, recombinant protein.

Recombinant Structural Maintenance Of Chromosomes Protein 3 (SMC3)
4-RPB146Hu01
  • EUR 521.12
  • EUR 242.00
  • EUR 1679.20
  • EUR 626.40
  • EUR 1152.80
  • EUR 412.00
  • EUR 4048.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: Q9UQE7
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 24.8kDa
  • Isoelectric Point: 6.1
Description: Recombinant Human Structural Maintenance Of Chromosomes Protein 3 expressed in: E.coli

Rotavirus A Non-structural glycoprotein 4
1-CSB-EP357389RIV
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 20.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Rotavirus A Non-structural glycoprotein 4,partial expressed in E.coli

Chikungunya virus Non-structural polyprotein，
1-CSB-EP810351CJAT
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 31.1 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Chikungunya virus Non-structural polyprotein，Partial expressed in E.coli

Rotavirus A Non-structural glycoprotein 4
1-CSB-YP366171ROH
  • EUR 679.00
  • EUR 335.00
  • EUR 2172.00
  • EUR 1051.00
  • EUR 1442.00
  • EUR 435.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 16.6 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Rotavirus A Non-structural glycoprotein 4,partial expressed in Yeast

Non-Structural Polyprotein Porf1 (ORF1) Antibody
20-abx300971
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Recombinant Measles Virus Non-Structural C-Protein (1-51)
7-07840 100µg Ask for price

Recombinant Measles Virus Non-Structural C-Protein (1-51)
7-07841 500µg Ask for price

Recombinant Measles Virus Non-Structural C-Protein (1-51)
7-07842 1000µg Ask for price

Mns1 ELISA Kit| Rat Meiosis-specific nuclear structural protein
EF018948 96 Tests
EUR 689

Mouse Structural maintenance of chromosomes protein 1B, Smc1b EL
ELI-42284m 96 Tests
EUR 865

Structural maintenance of chromosomes protein 4 (SMC4) Antibody (HRP)
20-abx337829
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
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Structural maintenance of chromosomes protein 4 (SMC4) Antibody (FITC)
20-abx337830
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
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Structural maintenance of chromosomes protein 4 (SMC4) Antibody (Biotin)
20-abx337831
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
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Structural Maintenance of Chromosomes Protein 3 (SMC3) Antibody (Biotin)
20-abx274285
  • EUR 439.00
  • EUR 244.00
  • EUR 1261.00
  • EUR 606.00
  • EUR 328.00
  • 100 ug
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  • 1 mg
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  • Shipped within 5-12 working days.

Human Structural maintenance of chromosomes protein 1B, SMC1B EL
ELI-41471h 96 Tests
EUR 824

Recombinant NiV Non-structural Protein V (aa 1-456)
VAng-Lsx05248-1mgEcoli 1 mg (E. coli)
EUR 5095
Description: Nipah Virus Non-structural protein V (P/V/C), recombinant protein.

Recombinant NiV Non-structural Protein V (aa 1-456)
VAng-Lsx05248-500gEcoli 500 µg (E. coli)
EUR 3597
Description: Nipah Virus Non-structural protein V (P/V/C), recombinant protein.

Recombinant NiV Non-structural Protein V (aa 1-456)
VAng-Lsx05248-50gEcoli 50 µg (E. coli)
EUR 2456
Description: Nipah Virus Non-structural protein V (P/V/C), recombinant protein.

Mouse Beaded Filament Structural Protein 1 (BFSP1) ELISA Kit
SEC329Mu-10x96wellstestplate 10x96-wells test plate
EUR 4862.4
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Beaded Filament Structural Protein 1 (BFSP1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inte
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Beaded Filament Structural Protein 1 (BFSP1) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Beaded Filament Structural Protein 1 (BFSP1) ELISA Kit
SEC329Mu-1x48wellstestplate 1x48-wells test plate
EUR 488.08
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Beaded Filament Structural Protein 1 (BFSP1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inte
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Beaded Filament Structural Protein 1 (BFSP1) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Beaded Filament Structural Protein 1 (BFSP1) ELISA Kit
SEC329Mu-1x96wellstestplate 1x96-wells test plate
EUR 654.4
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Beaded Filament Structural Protein 1 (BFSP1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inte
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Beaded Filament Structural Protein 1 (BFSP1) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Beaded Filament Structural Protein 1 (BFSP1) ELISA Kit
SEC329Mu-5x96wellstestplate 5x96-wells test plate
EUR 2644.8
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Beaded Filament Structural Protein 1 (BFSP1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inte
  • Show more
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Beaded Filament Structural Protein 1 (BFSP1) in Tissue homogenates, cell lysates and other biological fluids.

Mouse Beaded Filament Structural Protein 1 (BFSP1) ELISA Kit
4-SEC329Mu
  • EUR 4913.00
  • EUR 2595.00
  • EUR 655.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Beaded Filament Structural Protein 1 elisa. Alternative names of the recognized antigen: CP115
  • CP94
  • LIFL-H
  • Filensin
  • Lens fiber cell beaded-filament structural protein CP 115
  • Lens intermediate filament-like heavy
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Beaded Filament Structural Protein 1 (BFSP1) in samples from Tissue homogenates, cell lysates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Rotavirus A Non-structural glycoprotein 4 (NSP4)
1-CSB-EP465285ROJ
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 30.6 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Rotavirus A Non-structural glycoprotein 4(NSP4) ,partial expressed in E.coli

Avian infectious bursal disease virus Structural polyprotein
1-CSB-RP182094V
  • EUR 611.00
  • EUR 309.00
  • EUR 1827.00
  • EUR 939.00
  • EUR 1218.00
  • EUR 397.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 36.8 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Avian infectious bursal disease virus Structural polyprotein,partial expressed in E.coli

Rotavirus A Non-structural glycoprotein 4 (NSP4)
1-CSB-YP465285ROJ
  • EUR 679.00
  • EUR 335.00
  • EUR 2172.00
  • EUR 1051.00
  • EUR 1442.00
  • EUR 435.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 16.7 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Rotavirus A Non-structural glycoprotein 4(NSP4),partial expressed in Yeast

Structural Maintenance of Chromosomes 2 (SMC2) Antibody
abx025099-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes 2 (SMC2) Antibody
abx025099-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes 1A (SMC1A) Antibody
20-abx005309
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes 1A (SMC1A) Antibody
abx027456-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes 1A (SMC1A) Antibody
abx027456-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Structural Maintenance Of Chromosomes 6 (SMC6) Antibody
20-abx211117
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Structural Maintenance Of Chromosomes 2 (SMC2) Antibody
20-abx211391
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes 3 (SMC3) Antibody
20-abx115874
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes 5 (SMC5) Antibody
20-abx115875
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes 6 (SMC6) Antibody
20-abx115876
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes 2 (SMC2) Antibody
20-abx127053
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul
  • Shipped within 5-10 working days.

Mouse Renin 1 Structural (REN1) ELISA Kit
abx050254-96tests 96 tests
EUR 770
  • Shipped within 5-10 working days.

Structural Maintenance Of Chromosomes 1A (SMC1A) Antibody
abx159694-100ul 100 ul
EUR 467
  • Shipped within 5-10 working days.

Structural Maintenance Of Chromosomes 1A (SMC1A) Antibody
abx159695-100ul 100 ul
EUR 467
  • Shipped within 5-10 working days.

Structural Maintenance of Chromosomes 1A (SMC1A) Antibody
abx238016-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Moreover, the TPCC retention indicated values over 78% for murta juice, and 82% for arrayan juice. Similarly, the AA offered a rise over 2.1 occasions in relation to the correspondent preliminary AA worth. Thus, the method parameters values had been between 69% and 85% for effectivity, 70% and 88% for share of focus, and 0.72% and 0.88 (kg solutes/kg preliminary solutes) for solute yield. Therefore, this work gives perception about CBFC on helpful properties in recent Patagonian berries juices, for future functions in well being and industrial scale.