Endoplasmic reticulum retention and degradation of a mutation in SLC6A1 associated with epilepsy and autism.

Mutations in SLC6A1, encoding γ-aminobutyric acid (GABA) transporter 1 (GAT-1), have been recently associated with a spectrum of epilepsy syndromes, intellectual disability and autism in clinic. However, the pathophysiology of the gene mutations is far from clear.

Here we report a novel SLC6A1 missense mutation in a patient with epilepsy and autism spectrum disorder and characterized the molecular defects of the mutant GAT-1, from transporter protein trafficking to GABA uptake function in heterologous cells and neurons. The heterozygous missense mutation (c1081C to A (P361T)) in SLC6A1 was identified by exome sequencing. We have thoroughly characterized the molecular pathophysiology underlying the clinical phenotypes. We performed EEG recordings and autism diagnostic interview.

Mac-2BP Polyclonal Antibody

46771-50ul 50ul
EUR 187.00

Mac-2BP Polyclonal Antibody

ABP59179-003ml 0.03ml
EUR 158.00
  • Immunogen information: Synthesized peptide derived from part region of human Mac-2BP protein at amino acid sequence of 100-160
  • Applications tips:
Description: A polyclonal antibody for detection of Mac-2BP from Human, Mouse. This Mac-2BP antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human Mac-2BP protein at amino acid sequence of 100-160

Mac-2BP Polyclonal Antibody

ABP59179-01ml 0.1ml
EUR 289.00
  • Immunogen information: Synthesized peptide derived from part region of human Mac-2BP protein at amino acid sequence of 100-160
  • Applications tips:
Description: A polyclonal antibody for detection of Mac-2BP from Human, Mouse. This Mac-2BP antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human Mac-2BP protein at amino acid sequence of 100-160

Mac-2BP Polyclonal Antibody

ABP59179-02ml 0.2ml
EUR 414.00
  • Immunogen information: Synthesized peptide derived from part region of human Mac-2BP protein at amino acid sequence of 100-160
  • Applications tips:
Description: A polyclonal antibody for detection of Mac-2BP from Human, Mouse. This Mac-2BP antibody is for WB, ELISA. It is affinity-purified from rabbit serum by affinity-chromatography using the specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from part region of human Mac-2BP protein at amino acid sequence of 100-160

Mac-2BP Polyclonal Antibody

ES8657-100ul 100ul
EUR 279.00
Description: A Rabbit Polyclonal antibody against Mac-2BP from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Mac-2BP Polyclonal Antibody

ES8657-50ul 50ul
EUR 207.00
Description: A Rabbit Polyclonal antibody against Mac-2BP from Human/Mouse. This antibody is tested and validated for WB, ELISA, WB, ELISA

Anti-Mac-2BP antibody

STJ98720 200 µl
EUR 197.00
Description: Rabbit polyclonal to Mac-2BP.

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNUB0271-100 100uL
EUR 209.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271), Concentration: 0.2mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNUB0271-500 500uL
EUR 458.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271), Concentration: 0.2mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNUM0271-50 50uL
EUR 395.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271), 1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC040271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF405S conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC040271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF405S conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC610271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF660R conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC610271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF660R conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC470271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF647 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC470271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF647 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC550271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF555 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC550271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF555 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC050271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF405M conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC050271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF405M conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC400271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF640R conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC400271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF640R conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC430271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF543 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC430271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF543 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC800271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF680 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC800271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF680 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC810271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF680R conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC810271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF680R conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNCP0271-250 250uL
EUR 383.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),PerCP conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNCR0271-250 250uL
EUR 383.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),RPE conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNCA0271-250 250uL
EUR 383.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),APC conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNCAP0271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNCAP0271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNCH0271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNCH0271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC940271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF594 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC940271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF594 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC700271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF770 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC700271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF770 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNCB0271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),Biotin conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNCB0271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),Biotin conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC880271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF488A conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC880271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF488A conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC680271-100 100uL
EUR 199.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF568 conjugate, Concentration: 0.1mg/mL

CD11b / MAC-1 (Microglial Marker) (ITGAM/271) Antibody

BNC680271-500 500uL
EUR 544.00
Description: Primary antibody against CD11b / MAC-1 (Microglial Marker) (ITGAM/271),CF568 conjugate, Concentration: 0.1mg/mL

Mac-2BP Polyclonal Conjugated Antibody

C46771 100ul
EUR 397.00

Recombinant H9N2 MAC Hemagglutinin / HA Protein (aa 1-523) [His]

VAng-Wyb6928-100g 100 µg
EUR 1741.00
Description: Influenza A H9N2 (A/Chicken/Hong Kong/G9/97) Hemagglutinin / HA, recombinant protein.

Recombinant H9N2 MAC Hemagglutinin / HA Protein (aa 1-523) [His]

VAng-Wyb6928-50g 50 µg
EUR 1050.00
Description: Influenza A H9N2 (A/Chicken/Hong Kong/G9/97) Hemagglutinin / HA, recombinant protein.

Human membrane attack complex,MAC ELISA Kit

201-12-0360 96 tests
EUR 440.00
  • This membrane attack complex ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human membrane attack complex,MAC ELISA Kit

CN-04250H1 96T
EUR 442.00

Human membrane attack complex,MAC ELISA Kit

CN-04250H2 48T
EUR 293.00

Human Membrane Attack Complex (MAC) ELISA Kit

abx350654-96tests 96 tests
EUR 668.00
  • Shipped within 5-12 working days.

Human membrane attack complex(MAC)ELISA Kit

GA-E0376HM-48T 48T
EUR 289.00

Human membrane attack complex(MAC)ELISA Kit

GA-E0376HM-96T 96T
EUR 466.00

Human membrane attack complex(MAC)ELISA Kit

QY-E02156 96T
EUR 361.00

Rabbit membrane attack complex(MAC)ELISA Kit

QY-E30025 96T
EUR 374.00

Polyclonal Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) Antibody

AMM06021G 0.1mg
EUR 528.00
Description: A polyclonal antibody raised in Chicken that recognizes and binds to Human Integrin alpha-M (CD11b, MAC-1, OX-42 Antigen) . This antibody is tested and proven to work in the following applications:

Recombinant H9N2 MAC Hemagglutinin HA1 Subunit Protein (aa 1-338) [His]

VAng-Wyb6929-100g 100 µg
EUR 1741.00
Description: Influenza A H9N2 (A/Chicken/Hong Kong/G9/97) Hemagglutinin HA1 Subunit, recombinant protein.

Recombinant H9N2 MAC Hemagglutinin HA1 Subunit Protein (aa 1-338) [His]

VAng-Wyb6929-10g 10 µg
EUR 573.00
Description: Influenza A H9N2 (A/Chicken/Hong Kong/G9/97) Hemagglutinin HA1 Subunit, recombinant protein.

Recombinant H9N2 MAC Hemagglutinin HA1 Subunit Protein (aa 1-338) [His]

VAng-Wyb6929-50g 50 µg
EUR 1050.00
Description: Influenza A H9N2 (A/Chicken/Hong Kong/G9/97) Hemagglutinin HA1 Subunit, recombinant protein.

ELISA kit for Human MAC (Membrane Attack Complex)

E-EL-H5418 1 plate of 96 wells
EUR 534.00
  • Gentaur's MAC ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human MAC. Standards or samples are added to the micro ELISA plate wells and combined with the
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Human MAC (Membrane Attack Complex) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human Membrane attack complex (MAC)

KTE62641-48T 48T
EUR 354.00
  • Protectin, a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 a
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Membrane attack complex (MAC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Membrane attack complex (MAC)

KTE62641-5platesof96wells 5 plates of 96 wells
EUR 2252.00
  • Protectin, a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 a
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Membrane attack complex (MAC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human Membrane attack complex (MAC)

KTE62641-96T 96T
EUR 572.00
  • Protectin, a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 a
  • Show more
Description: Quantitative sandwich ELISA for measuring Human Membrane attack complex (MAC) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Monoclonal CD11b / MAC-1 (Microglial Marker) Antibody - With BSA and Azide, Clone: C11b/660

APG03040G 0.05mg
EUR 396.00
Description: A Monoclonal antibody against Human CD11b / MAC-1 (Microglial Marker) - With BSA and Azide. The antibodies are raised in Mouse and are from clone C11b/660. This antibody is applicable in IHC, IF, FC, IP, E

Monoclonal CD11b / MAC-1 (Microglial Marker) Antibody - Without BSA and Azide, Clone: M1/70

APG03041G 0.1mg
EUR 484.00
Description: A Monoclonal antibody against Human CD11b / MAC-1 (Microglial Marker) - Without BSA and Azide. The antibodies are raised in Rat and are from clone M1/70. This antibody is applicable in IF, FC

Monoclonal CD11b / MAC-1 (Microglial Marker) Antibody - Without BSA and Azide, Clone: C11b/660

APG03042G 0.1mg
EUR 484.00
Description: A Monoclonal antibody against Human CD11b / MAC-1 (Microglial Marker) - Without BSA and Azide. The antibodies are raised in Mouse and are from clone C11b/660. This antibody is applicable in IF, FC

Monoclonal CD11b / MAC-1 (Microglial Marker) Antibody - With BSA and Azide, Clone: M1/70

AMM05473G 0.05mg
EUR 396.00
Description: A Monoclonal antibody against Human CD11b / MAC-1 (Microglial Marker) - With BSA and Azide. The antibodies are raised in Rat and are from clone M1/70. This antibody is applicable in IHC, IF, FC, IP, E

Monoclonal MAC-2-BP / LGALS3BP Antibody (clone 2B1), Clone: 2B1

AMM02212G 0.05ml
EUR 484.00
Description: A Monoclonal antibody against Human MAC-2-BP / LGALS3BP (clone 2B1). The antibodies are raised in Mouse and are from clone 2B1. This antibody is applicable in WB and IHC-P, Flo

Recombinant Human CD59/ CD59A/ MAC-IP Protein, GST, E.coli-100ug

QP5791-ec-100ug 100ug
EUR 408.00

Recombinant Human CD59/ CD59A/ MAC-IP Protein, GST, E.coli-10ug

QP5791-ec-10ug 10ug
EUR 200.00

Recombinant Human CD59/ CD59A/ MAC-IP Protein, GST, E.coli-1mg

QP5791-ec-1mg 1mg
EUR 1632.00

Recombinant Human CD59/ CD59A/ MAC-IP Protein, GST, E.coli-200ug

QP5791-ec-200ug 200ug
EUR 634.00

Recombinant Human CD59/ CD59A/ MAC-IP Protein, GST, E.coli-500ug

QP5791-ec-500ug 500ug
EUR 1060.00

Recombinant Human CD59/ CD59A/ MAC-IP Protein, GST, E.coli-50ug

QP5791-ec-50ug 50ug
EUR 263.00

Recombinant Human CD59/ CD59A/ MAC-IP Protein, His, Yeast-100ug

QP5791-ye-100ug 100ug
EUR 480.00

Recombinant Human CD59/ CD59A/ MAC-IP Protein, His, Yeast-10ug

QP5791-ye-10ug 10ug
EUR 236.00

Recombinant Human CD59/ CD59A/ MAC-IP Protein, His, Yeast-1mg

QP5791-ye-1mg 1mg
EUR 1885.00

Recombinant Human CD59/ CD59A/ MAC-IP Protein, His, Yeast-200ug

QP5791-ye-200ug 200ug
EUR 744.00

Recombinant Human CD59/ CD59A/ MAC-IP Protein, His, Yeast-500ug

QP5791-ye-500ug 500ug
EUR 1206.00

Recombinant Human CD59/ CD59A/ MAC-IP Protein, His, Yeast-50ug

QP5791-ye-50ug 50ug
EUR 299.00

Neuregulin/Heregulin-1? (NRG-1?/HRG-1?), human recombinant protein

P1054-1 1 mg
EUR 3947.00
Description: Neuregulin (NRG) is a signaling protein for ErbB2/ErbB4 receptor heterodimers on the cardiac muscle cells and plays an important role in heart structure and function through inducing cardiomyocyte differentiation

Angiotensin 1/2 (1-7) amide

A1054-1 1 mg
EUR 96.00
Description: Angiotensin I/II (1-7) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-amide) is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse.

Angiotensin 1/2 (1-8) amide

A1055-1 1 mg
EUR 96.00
Description: The physiologically active peptide angiotensin-2 (angiotensin 1- 8) is yielded from angiotensin-1, a substrate of ACE (angiotensin converting enzyme), by removing a dipeptide.

Endothelin-1 (1-15), amide, human

A1111-1 1 mg
EUR 722.00
Description: Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium and have a key role in vascular homeostasis.

Haptoglobin, (Phenotype 1-1) Human Plasma

7536-1
EUR 321.00

TAPI-1

2068-1
EUR 398.00

IDE-1

2193-1
EUR 147.00

PFI-1

2203-1
EUR 115.00

IQ-1

1663-1
EUR 204.00

Shz-1

1915-1
EUR 137.00

1-Azakenpaullone

1944-1
EUR 289.00

StemRegenin 1

1967-1
EUR 147.00

SANT-1

1978-1
EUR 126.00

4EGI-1

B2901-1
EUR 142.00

TAPI-1

B4686-1 1 mg
EUR 268.00
Description: TAPI-1 is an inhibitor of tumour necrosis factor with IC50 value of 8.09 ?M [1].TAPI-1 is an inhibitor of TACE/ADAM17 which catalyzes the cleavage of full-length APP to the soluble N-terminal fragment (sAPP?).

C14TKL-1

B5240-1 1 mg
EUR 399.00

?1-MSH

B5427-1 1 mg
EUR 268.00

MMK 1

B5446-1 1 mg
EUR 268.00

CRSP-1

B5452-.1 100 ug
EUR 415.00

ADWX 1

B5722-.1 100 ug
EUR 583.00
Description: ADWX 1 is a potent and selective inhibitor of KV1.3 channel with IC50 values of 1.89 pM and 0.65 nM for Kv1.3 and Kv1.1, respectively [1].

Purotoxin 1

B5771-.1 100 µg
EUR 380.00

Shz 1

B5772-1 1 mg
EUR 118.00

Psalmotoxin 1

B5796-.1 100 ug
EUR 447.00
Description: IC50: 0.9 nMPsalmotoxin 1 is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker.Several ASIC subunits described: ASIC1a, ASIC1b, ASIC2a, ASIC2b, and ASIC3 with different kinetics, tissue distribution, and external pH sensitivities.

UK 1

C5006-1 1 mg
EUR 363.00
Description: UK 1, an unusual bis-benzoxazole metabolite isolated from Streptomyces sp. 517-02, is an inhibitor of topoisomerase II (Topo II) and hepatitis C viral replication.

KP372-1

C5053-1 1 mg
EUR 132.00
Description: IC50: 30-60 nM for thyroid cancer cells KP372-1 is a specific Akt inhibitor. The phosphatidylinositol 3' kinase (PI3K)/phosphatase, which is a key regulator of cell proliferation and survival, is mutated or activated in various cancers.

Flutax 1

B6986-1 1 mg
EUR 399.00

IDE 1

B7566-1 1 mg
EUR 118.00

Rbin-1

B7823-1 1 mg
EUR 154.00
Description: Rbin-1 is an eukaryotic ribosome assembly inhibitor.All cellular proteins are synthesized by ribosomes, whose biogenesis is a complex multi-step process quickly completed in eukaryotes.

CMPD-1

B2991-1 1mg
EUR 125.00

Anti-HO-1 Monoclonal Antibody (HO-1-2)

M00253-1 1mg
EUR 397.00
Description: Mouse Monoclonal HO-1 Antibody (HO-1-2). Validated in Flow Cytometry, IHC, WB and tested in Human, Mouse, Rat.

IL-1-beta Interleukin-1 betaHuman Recombinant Protein

PROTP01584-1 Regular: 10ug
EUR 317.00
Description: Interleukin-1 beta Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton.;The IL-1b is purified by proprietary chromatographic techniques.

MMP-1 Matrix Metalloproteinase-1 Human Recombinant Protein

PROTP03956-1 Regular: 20ug
EUR 317.00
Description: MMP 1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 393 amino acids (100-469a.a) and having a molecular mass of 45kDa. MMP 1 is fused to a 23 amino acid His-tag at N-terminus.

EZSolution? TAPI-1

2537-1
EUR 381.00

(R)-Perharidine-1

2615-1
EUR 164.00

Akt-I-1

B1610-1
EUR 185.00

TASIN-1 hydrochloride

B2088-1
EUR 142.00

1-NM-PP1

B2346-1
EUR 142.00

CDK7-IN-1

B4665-1 1 mg
EUR 358.00

LPA2 antagonist 1

B4726-1 1 mg
EUR 319.00

PACAP 1-27

B5075-1 1 mg
EUR 290.00

Nociceptin (1-7)

B5087-1 1 mg
EUR 399.00

Hemokinin 1 (mouse)

B5127-1 1 mg
EUR 321.00

GIP (1-39)

B5280-1 1 mg
EUR 609.00

JMV 390-1

B5317-1 1 mg
EUR 242.00

Hemokinin 1 (human)

B5318-1 1 mg
EUR 340.00

Echistatin, ?1 isoform

B5391-.1 100 ug
EUR 583.00

HPGDS inhibitor 1

B1046-1 1 mg
EUR 181.00
Description: HPGDS inhibitor 1 is an oral potent and selective inhibitor of hematopoietic prostaglandin D synthase (HPGDS) with IC50 value of 0.7nM [1].Prostaglandin D2 (PGD2) is a mediator of allergy and inflammation.

Teicoplanin A3-1

C4943-1 1 mg
EUR 326.00
Description: Teicoplanin A3-1, also known as Antibiotic L 17054, is a glycopeptide antibiotic derived from Actinoplanes teichomyceticus and produces a potent broad spectrum antibiotic activity against gram-positive bacteria.

RN-1 (hydrochloride)

C4247-1 1 mg
EUR 112.00
Description: RN-1 (hydrochloride) is a brain-penetrant, potent and irreversible LSD1 inhibitor with IC50 values of 10-70 nM [1]. Lysine-specific demethylase 1 (LSD1) is a flavin-dependent monoamine oxidase that demethylate mono- and di-methylated lysines, specifically histone 3, lysines 4 and 9.

IDO-IN-1

C3211-1 1 mg
EUR 139.00
Description: IC50: 59 nMIDO-IN-1 is an indoleamine-2,3-dioxygenase (IDO) inhibitor.

StemRegenin 1 (hydrochloride)

C3551-1 1 mg
EUR 118.00
Description: IC50: 127 nM in CD34+ cellsStemRegenin 1 is an aryl hydrocarbon receptor signaling antagonist.The aryl hydrocarbon receptor (AhR ) is a protein that is encoded by the AHR gene.

PACAP 1-38

B6625-1 1 mg
EUR 347.00

Sphingosine-1-phosphate

B6707-1 1 mg
EUR 181.00
Description: Sphingosine-1-phosphate is an endogenous second messenger that involved in cell proliferation and survival and is a ligand for S1PR1 [1] [2].

SL 0101-1

B9008-1 1 mg
EUR 163.00

(1-328) RAD51D (1-328 a.a.) Human Recombinant Protein

PROTO75771-1 Regular: 10ug
EUR 317.00
Description: RAD51D (1-328) Human Recombinant produced in E. coli is. a single polypeptide chain containing 351 amino acids and having a molecular mass of 37.4kDa. RAD51D (1-328) is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

XMIR-1 RNA oligo miRNA-1-3p with Xmotif

XMIR-1 10 rxn
EUR 438.00
  • Category: Exosome

AXMIR-1 RNA oligo anti-miRNA-1-3p with Xmotif

AXMIR-1 10 reactions
EUR 438.00
  • Category: Exosome

Human KRAB-associated Protein 1 (KAP-1) AssayMax ELISA Kit

EK2802-1 96 Well Plate
EUR 477.00

Human Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit

EI2200-1 96 Well Plate
EUR 477.00

Human Interleukin-1-alpha (IL-1-alpha) AssayMax ELISA Kit

EI2301-1 96 Well Plate
EUR 477.00

Mouse Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit

EMI2200-1 96 Well Plate
EUR 477.00

Human Plasminogen Activator Inhibitor-1 (PAI-1) AssayMax ELISA Kit

EP1100-1 96 Well Plate
EUR 417.00

Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378

M04431-1 100uL
EUR 385.00
Description: Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 tested in WB, IHC, reactive to Human

GAD1 iso1 Glutamate Decarboxylase 1 Isoform-1 Human Recombinant Protein

PROTQ99259-1 Regular: 20ug
EUR 317.00
Description: GAD1 iso1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 617 amino acids (1-594 a.a) and having a molecular mass of 69.3kDa. GAD1 iso1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Envelope-1, Dengue Virus Subtype 1 Recombinant Protein, Insect Cells

PROTB1PNJ5-1 Regular: 10ug
EUR 317.00
Description: Recombinant Dengue Virus Subtype 1 produced in Insect Cells is a polypeptide chain containing amino acids 281-675 and having a molecular weight of approximately 50kDa. ;Dengue Envelope-1 is purified by proprietary chromatographic technique.

TGF-b-1 Transforming Growth Factor-beta 1 Human protein

PROTP01137-1 Regular: 2.5ug
EUR 1157.00
Description: Human Transforming Growth Factor-beta 1 purified from Human Platelets having a molecular mass of 25kDa.;The TGF-b 1 is purified by proprietary chromatographic techniques.

MCP-1 Monocyte Chemotactic Protein-1 Mouse Recombinant Protein (CCL2)

PROTP10148-1 Regular: 10ug
EUR 317.00
Description: Monocyte Chemotactic Protein-1 Mouse Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 125 amino acids and having a molecular mass of 14 kDa. ;The MCP-1 is purified by proprietary chromatographic techniques.

MCP-1 Monocyte Chemotactic Protein-1 Human Recombinant Protein (CCL2)

PROTP13500-1 Regular: 20ug
EUR 317.00
Description: Monocyte Chemotactic Protein-1 Human Recombinant also known as Monocyte Chemotactic and Activating Factor (MCAF) produced in E.Coli is a non-glycosylated, Polypeptide chain containing 76 amino acids and having a molecular mass of 8.6kDa. ;The MCP-1 is purified by proprietary chromatographic techniques.

StemRegenin 1, Free base

2642-1
EUR 131.00

Anti-Periphilin 1 Antibody

A06996-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse.

Anti-Lyl-1 Antibody

A07491-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-GLI-1 Antibody

A07972-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for GLI-1 Antibody (ACSS1) detection. Tested with WB in Human, Mouse, Rat.

Anti-Cerebellin 1 Antibody

A09176-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for Cerebellin 1 Antibody (CBLN1) detection. Tested with WB in Human, Mouse, Rat.

Anti-DOC-1 Antibody

A09467-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for DOC-1 Antibody (CDK2AP1) detection. Tested with WB in Human, Mouse.

Beta-Amyloid (1-11)

A1002-1 1 mg
EUR 102.00
Description: Beta-amyloid (1-11) (Abeta or A?) (C56H76N16O22) is a peptide with the sequence H-{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}-OH,which is processed from the Amyloid precursor protein.

Amyloid ?-Protein (1-15)

A1003-1 1 mg
EUR 113.00
Description: Beta-amyloid protein (A beta), a 39-43 amino acid peptide composed of a portion of the transmembrane domain and the extracellular domain of the amyloid precursor protein (APP), is also the principal component of amyloid.

ANP (1-11), rat

A1009-1 1 mg
EUR 84.00
Description: Atrial Natriuretic Peptide (ANP) (C49H84N20O15S) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide that is synthesized, stored, and released by atrial myocytes in response to atrial distension, endothelin, and sympathetic stimulation.

alpha-1 antitrypsin fragment

A1051-1 1 mg
EUR 108.00
Description: Alpha-1 antitrypsin (A1AT) (H2N-Leu-Gln-His-Leu-Glu-Asn-Glu-Leu-Thr-His-Asp-Ile-Ile-Thr-Lys-OH), which is known as serum trypsin inhibitor, is a protease inhibitor belonging to the serpin superfamily.

BNP (1-32), human

A1105-1 1 mg
EUR 177.00
Description: Basic natriuretic peptide (BNP), now known as B-type natriuretic peptide (also BNP) or GC-B, is a 32 amino acid polypeptide secreted by the ventricles of the heart in response to excessive stretching of heart muscle cells (cardiomyocytes).

Anti-NPDC-1 Antibody

A12846-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for NPDC-1 Antibody (NPDC1) detection. Tested with WB in Human, Mouse, Rat.

Anti-CNG-1 Antibody

A05494-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat.

B-Raf IN 1

B4727-1 1 mg
EUR 118.00

Nociceptin (1-13)NH2

B5102-1 1 mg
EUR 184.00

JIP-1 (153-163)

B5130-1 1 mg
EUR 399.00

Nogo-66 (1-40)

B5247-1 1 mg
EUR 609.00

Orphanin FQ (1-11)

B5497-1 1 mg
EUR 226.00

Anti-Flk-1 Antibody

A00901-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse.

Anti-EDG-1 Antibody

A01502-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat.

Anti-ROBO-1 Antibody

A01530-1 100ug
EUR 455.00
Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Bag-1 Antibody

A02423-1 50 ul
EUR 397.00
Description: Rabbit Polyclonal Bag-1 Antibody. Validated in IP, IHC and tested in Bovine, Canine, Human, Mouse, Rat.

Anti-TUB 1 Antibody

A02917-1 100ug/vial
EUR 294.00

Anti-Dok-1 Antibody

A03039-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for Dok-1 Antibody (DOK1) detection.tested for WB in Human, Mouse, Rat.

Anti-TFIIIB90-1 Antibody

A03761-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse.

Anti-Atrophin-1 Antibody

A03828-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat.

Anti-PARP-1 Antibody

A00122-1 100ul
EUR 397.00
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse.

Anti-Presenilin 1 Antibody

A00138-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat.

Anti-PAI-1 Antibody

A00637-1 100ul
EUR 397.00
Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat.

dNTP Mix (1 ml)

9002-1
EUR 153.00

R-1 Methanandamide Phosphate

C3352-1 1 mg
EUR 126.00
Description: R-1 Methanandamide Phosphate,a water soluble prodrug analog of AEA, exhibited similar activity to that of AEA in the growth inhibition of C6 glioma cells[1]. Arachidonoyl ethanolamide (AEA) was the first endogenous cannabinoid (CB).

Ginkgolic Acid C15:1

C3421-1 1 mg
EUR 118.00
Description: Ginkgolic acid is an alkylphenol derivative that causes allergic skin inflammation. IC50 values of ginkgolic acid against the SUMOylation of RanGAP1-C2 are 3.0 ?M. Ginkgolic Acid, a Major Component of Ginkgo biloba Extract, inhibited SUMOylation in vitro and in vivo [1].

Individual Reaction Mix 1

G065-1 200 reactions
EUR 167.00

IGF-1, human recombinant

P1016-.1 100 µg
EUR 763.00
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue

Supercoiled pHOT-1 DNA

TG2030-1 25 ug
EUR 246.00

Relaxed pHOT-1 DNA

TG2035-1 25 ug
EUR 246.00

Human Heat Shock Factor Protein 1 (HSF 1) AssayMax ELISA kit

EH5215-1 96 Well Plate
EUR 417.00

Human Insulin-like Growth Factor 1 (IGF-1) AssayMax ELISA Kit

EI1001-1 96 Well Plate
EUR 477.00

Mouse Insulin-like Growth Factor 1 (IGF-1) AssayMax ELISA Kit

EMI1001-1 96 Well Plate
EUR 477.00

VAMP2 (1-94) Synaptobrevin-2 (1-94 a.a) Human Recombinant Protein

PROTP63027-1 Regular: 5ug
EUR 317.00
Description: VAMP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 118 amino acids (1-94 a.a) and having a molecular mass of 12.8kDa.;VAMP2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

IL1RL1 Human, Interleukin-1 Receptor Like-1 Human Recombinant Protein, Sf9

PROTQ01638-1 Regular: 10ug
EUR 317.00
Description: IL 1RL1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (19-328 a.a.) and fused to an 8 aa His Tag at C-terminus containing a total of 318 amino acids and having a molecular mass of 36.0kDa.;IL 1RL1 shows multiple bands between 40-57kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.