Month: May 2020

The gene for the embryonic stem cell coactivator UTF1 carries a regulatory element which selectively interacts with a complex composed of Oct-3/4 and Sox-2.

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The gene for the embryonic stem cell coactivator UTF1 carries a regulatory element which selectively interacts with a complex composed of Oct-3/4 and Sox-2.

UTF1 is a transcriptional coactivator which has lately been remoted and discovered to be expressed primarily in pluripotent embryonic stem (ES) cells (A. Okuda, A. Fukushima, M. Nishimoto, et al., EMBO J. 17:2019-2032, 1998). To acquire perception into the regulatory community of gene expression in ES cells, we’ve got characterised the regulatory parts governing UTF1 … Read more

The Arabidopsis CBF gene family is composed of three genes encoding AP2 domain-containing proteins whose expression Is regulated by low temperature but not by abscisic acid or dehydration.

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The Arabidopsis CBF gene family is composed of three genes encoding AP2 domain-containing proteins whose expression Is regulated by low temperature but not by abscisic acid or dehydration.

We have recognized two genes from Arabidopsis that present excessive similarity with CBF1, a gene encoding an AP2 domain-containing transcriptional activator that binds to the low-temperature-responsive factor CCGAC and induces the expression of some cold-regulated genes, rising plant freezing tolerance. These two genes, which we’ve got named CBF2 and CBF3, additionally encode proteins containing AP2 … Read more

Gene composer: database software for protein construct design, codon engineering, and gene synthesis.

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Gene composer: database software for protein construct design, codon engineering, and gene synthesis.

BACKGROUNDTo enhance effectivity in excessive throughput protein construction dedication, we have now developed a database software package deal, Gene Composer, which facilitates the information-rich design of protein constructs and their codon engineered artificial gene sequences. With its modular workflow design and quite a few graphical consumer interfaces, Gene Composer permits researchers to carry out all … Read more